TLC Pharma Lab: June 2015

Atorvastatin Dihydroxy Epoxy Impurity

Impurity:Atorvastatin Dihydroxy Epoxy Impurity
Chemical Name:4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo [3.1.0]hexane-1-carboxamide

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Atorvastatin Epoxy Tetrahydrofuran Analog impurity

Atorvastatin Epoxy Tetrahydrofuran Analog

Impurity:Atorvastatin Epoxy Tetrahydrofuran Analog impurity
Chemical Name:4-(4-Fluorophenyl)-2,4-dihydroxy-2-isopropyl-N,5-diphenyl-3,6-dioxabicyclo [3.1.0]hexane-1-carboxamide

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Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog impurity

Impurity:Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog impurity
Chemical Name:2,6-(2-Carboxymethyl-3-oxapropano)-7,8-epoxy-8a-(4-fluorophenyl)-6-isopropyl-N,8-diphenylhexahydro-2H -pyrrolo[2,1-b][1,3]oxazine-7-carboxamide

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Atorvastatin Pyrrolidone Analog

Impurity:Atorvastatin Pyrrolidone Analog impurity
Chemical Name:(3R,5R)-7-[5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-1H-pyrrol

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Atorvastatin Lactam impurity

Atorvastatin Lactam

Impurity:Atorvastatin Lactam Impurity
Chemical Name:(3R,5R)-7-[5-(4-Fluorophenyl)-2,3-dihydro-3-(1-methylethyl)-2-oxo-4-phenyl-3-[(phenylamino)carbonyl]-1H-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid

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Atorvastatin Cyclic 6-Hydroxy Impurity

Impurity:Atorvastatin Cyclic 6-Hydroxy Impurity
Chemical Name:4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H

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Atorvastatin Epoxy Pyrrolooxazin Analog

Impurity:Atorvastatin Epoxy Pyrrolooxazin Analog
Chemical Name:4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H

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Atorvastatin Cyclic Isopropyl Impurity

Impurity:Atorvastatin Cyclic Isopropyl Impurity
Chemical Name:4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H

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Atorvastatin FXA Impurity

Impurity:Atorvastatin Impurity
Chemical Name:4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl-7-phenyl-8-(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}

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Atorvastatin Cyclic FP impurity | Atorvastatin Cyclic EP impurity

Atorvastatin Cyclic 7-Hydroxy Impurity

Impurity:Atorvastatin Impurity
Chemical Name:1b-(4-Fluorophenyl)hexahydro-β,7-dihydroxy-7-(1-methylethyl)-1a-phenyl-7a-[(phenylamino)carbonyl]-3H-oxireno[3,4]pyrrolo[2,1-b][1,3]oxazine
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Atorvastatin Cyclic Fluorophenyl Impurity

Atorvastatin FX1 Impurity

Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog impurities

Atorvastatin Epoxy Pyrrolooxazin Tricyclic Analog

Impurity:Atorvastatin Impurity
Chemical Name:2,6-(2-Carboxymethyl-3-oxapropano)-7,8-epoxy-8a-(4-fluorophenyl)-6-isopropyl-N,8-diphenylhexahydro-2H -pyrrolo[2,1-b][1,3]oxazine-7-carboxamide.

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Atorvastatin impurities

Impurity:Atorvastatin Cyclic Isopropyl Impurity or Atorvastatin Epoxy Pyrrol
Chemical Name:4-{6-(4-Fluorophenyl)-7,8-epoxy-6-hydroxy-8a-isopropyl7phenyl8(phenylcarbamoyl)hexahydro-2H -pyrrolo[2,1-b][1,3]oxazin-2-yl}

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Thursday, 25 June 2015